Andrew Garfield

Spider-Man / Peter Parker

Emma Stone

Gwen Stacy

Rhys Ifans

The Lizard / Dr. Curt Connors

Denis Leary

Captain Stacy

Martin Sheen

Uncle Ben

Sally Field

Aunt May

Irrfan Khan

Rajit Ratha

Campbell Scott

Richard Parker

Embeth Davidtz

Mary Parker

Chris Zylka

Flash Thompson

Max Charles

Peter Parker (Age 4)

C. Thomas Howell

Jack's Father

Jake Keiffer

Jack

Kari Coleman

Helen Stacy

Michael Barra

Store Clerk

Leif Gantvoort

Cash Register Thief

Andy Pessoa

Gordon

Hannah Marks

Missy Kallenback

Kelsey Asbille

Hot Girl

Kevin McCorkle

Mr. Cramer