James McAvoy

Patricia / Dennis / Hedwig / The Beast / Barry / Heinrich / Jade / Ian / Mary Reynolds / Norma / Jalin / Kat / B.T. / Kevin Wendell Crumb / Mr. Pritchard / Felida / Luke / Goddard / Samuel / Polly

Bruce Willis

David Dunn / The Overseer

Samuel L. Jackson

Elijah Price / Mr. Glass

Sarah Paulson

Dr. Ellie Staple

Anya Taylor-Joy

Casey Cooke

Spencer Treat Clark

Joseph Dunn

Charlayne Woodard

Mrs. Price

Luke Kirby

Pierce

Adam David Thompson

Daryl

Shannon Destiny Ryan

Cheerleading Girl

Diana Silvers

Cheerleading Girl

Nina Wisner

Cheerleading Girl

Kyli Zion

Cheerleading Girl

Serge Didenko

Ronald, Powerful Young Man

Russell Posner

T, Skinny Camera Kid

Kimberly S. Fairbanks

Assistant Principal

Rosemary Howard

Penelope Crumb

Bryan McElroy

Clarence Crumb

Owen Vitullo

Young Kevin

William Turner

Young Elijah