Clint Eastwood

Manco

Lee Van Cleef

Col. Douglas Mortimer

Gian Maria Volonté

El Indio

Luigi Pistilli

Groggy, Member of Indio's Gang

Klaus Kinski

Juan Wild - The Hunchback

Joseph Egger

Old Prophet

Panos Papadopulos

Sancho Perez, Member of Indio's Gang

Mara Krupp

Mary

Benito Stefanelli

Luke 'Hughie'

Roberto Camardiel

Tucumcari Station Clerk

Aldo Sambrell

Cuchillo

Luis Rodríguez

Manuel, Member of Indio's Gang

Tomás Blanco

Tucumcari Sheriff

Lorenzo Robledo

Tomaso, Indio's Traitor

Sergio Mendizábal

Tucumcari Bank Manager

Dante Maggio

Carpenter in Cell with El Indio

Diana Rabito

Callaway's Beautiful Girl in Tub

Giovanni Tarallo

Santa Cruz Telegraphist

Mario Meniconi

Train Conductor

Mario Brega

Niño, Member of Indio's Gang